本課程針對小分子藥物開發策略,以BIOVIA Discovery Studio 2020作工具,說明分子對接、基於片段的藥物優化設計及QSAR的應用及操作方法。
課程內容安排:
1.Introduction to drug discovery and computer aided drug design
2.Introduction to discovery studio
3.Ligand docking with CDOCKER
4.Scaffold hopping to identify replacement fragments for lead optimization
5.Working with QSAR
6.Hands-on實機操作教學