|
1. Introduction to Protein-Based Modeling
2. Assessing the limitations and assumptions in protein homology modeling
3. Selecting an appropriate protein structural template to create a model
4. Aligning your protein target sequence to a protein template sequence
5. Building a protein homology model
6. Analyzing the model in terms of quality, energy and structural features
7. Refining the homology model
8. Using the homology model for further studies, including mutagenesis studies,
protein-protein docking, or ligand docking for structure-based drug design
- protein-protein docking: ZDOCK and analysis
- refining the poses: RDOCK
9. Hands-on實機操作教學
|
